These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. The dose of Ferinject is based on calculation of ideal body weight and calculation of iron deficit using the Ganzoni formula. calcium carbonate decreases levels of iron sucrose by inhibition of GI absorption. Separate dosing of tetracyclines from these products. Indicated for treatment of iron deficiency anemia associated with chronic kidney disease, Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week, Non-dialysis-dependent CKD: 200 mg IV injection for 5 doses in over 14 days (cumulative 1000 mg in 14-day period), Peritoneal dialysis-dependent CKD: 300 mg IV infusion (1.5 hr) for 2 doses 14 days apart, THEN 400 mg IV infusion (2.5 hr) 14 days later (cumulative 1000 mg divided in 3 doses/week), Indicated for maintenance treatment of iron-deficient anemia associated with chronic kidney disease, <2 years: Safety and efficacy not established, Iron replacement treatment in pediatric patients has not been established. This information does not assure that this product is safe, effective, or appropriate for you. Deferasirox chelates iron. This site contains information for licensed healthcare professionals in the United States. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. Minor/Significance Unknown. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. Use Caution/Monitor. Minor/Significance Unknown. Serious - Use Alternative (1)iron sucrose decreases levels of minocycline by inhibition of GI absorption. 4. Many patients with kidney disease cannot get enough iron from food and require injections. 1. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. This health tool computes the required parenteral iron replacement dose for the iron deficit extracted from the patient weight and hemoglobin level from complete blood count test. Minor/Significance Unknown. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Separate by 2 hr. Koch TA, Myers J, Goodnough LT. Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Serious - Use Alternative (1)iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. PDF Protocol for the use of Intravenous Iron Sucrose (Venofer Challenges in the treatment of iron deficiency include finding and addressing the underlying cause and the selection of an iron replacement product that meets the needs of the patient. Iron Deficiency Calculator Although the original formula requires the weight in kilograms, values input in lbs are transformed. Minor/Significance Unknown. ONE DOSE. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. The initial hemoglobin rise is more rapid with parenteral iron but on the long term (12 weeks), both therapies reach similar levels of hemoglobin. The therapeutic management of IDA focuses on the replenishment of the iron stores through methods that have been mentioned above. . Max Dose. Copyright 1993-2021 By clicking send, you acknowledge that you have permission to email the recipient with this information. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. Most Use Caution/Monitor. calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. Avoid or Use Alternate Drug. The dosage of Venofer is expressed in mg of elemental iron. ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. All adult and pediatric patients receiving Venofer require periodic monitoring of hematologic and iron parameters (hemoglobin, hematocrit, serum ferritin and transferrin saturation). 300-500 mg Iron Sucrose in NS 250 mL administered over three (3) hours; may repeat as needed in 3-7 days to reach 1 gm. We comply with the HONcode standard for trustworthy health information. prescription products. Ganzoni AM. Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD): Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl x 15 minutes. IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. Minor/Significance Unknown. Administer on 5 different occasions over a 14 day period. Corrected Calcium. Included in the iron dextran package insert. omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. iron sucrose decreases levels of ciprofloxacin by inhibition of GI absorption. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Accessed: 4/12/2011. Monitor Closely (1)deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. Avoid or Use Alternate Drug. In this study and another study evaluating a single intravenous dose of iron sucrose containing 500-700 mg of iron in 26 anemic patients on erythropoietin therapy (23 female, 3 male; age range 16-60), approximately 5% of the iron was . Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL) -Hgb deficit (g/dL) = 14.0 - patient hgb conc. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. View the formulary and any restrictions for each plan. Use Caution/Monitor. HOW TO USE: This medication is given by injection into a vein as directed by your doctor. Iron sucrose: 20 mg/mL. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Venofer (iron sucrose) dose calculator | Calculosaurus.com Clinical calculators for obstetrics and gynaecology VTE risk assessment Calculator menu Venofer dose calculator Iron sucrose Not what you were looking for? Interaction only with oral iron administration. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Monitor Closely (1)dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. INFeD is given undiluted at a slow gradual rate not to exceed 50 mg (1 mL) per minute. Venofer (Iron Sucrose Injection): Uses, Dosage, Side Effects - RxList Administer a test INFeD dose prior to the first therapeutic dose. Iron sucrose: 20 mg/mL. Either increases effects of the other by pharmacodynamic synergism. Oral and parenteral products - see background option for oral products. Pregnancy: Risk Summary-Clinical Considerations. Minor/Significance Unknown. Recommended Treatment Regimen Using IV Iron Sucrose for Initial Repletion in Children With Iron Deficiency Anemia. Separate dosing of tetracyclines from these products. Applies only to oral form of both agents. Give each dose as 750 mg for a total cumulative dose of 1500 mg of iron per course. Anemias. J Med. Avoid or Use Alternate Drug. iron sucrose decreases levels of methyldopa by inhibition of GI absorption. May increase risk of hypotension. Adult Dosage and Administration: The recommended dosage of Ferrlecit for the repletion treatment of iron deficiency in hemodialysis patients is 10 mL of Ferrlecit (125 mg of elemental iron). 2. Minor/Significance Unknown. iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. Excessive dosages of Venofer may lead to accumulation of iron in storage sites potentially leading to hemosiderosis. Copyright 2021 GlobalRPH - Web Development by, Calculation of the Total Iron Deficit Alternative equation. Dosage Calculator - [100% Free] - Calculators.io INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Anaphylaxis may occur with IV iron and resuscitation facilities should be available.11 It would appear that iron polymaltose may have a higher incidence of severe systemic reactions than iron sucrose and ferric carboxymaltose. 1974 Jun;31(6):592-5. Use Caution/Monitor. Monitor for signs and symptoms of hypotension following each administration of Venofer. Applies only to oral form of both agents. Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. Clinical use of the total dose intravenous infusion of iron dextran. Use Caution/Monitor. deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. Venofer must only be administered intravenously either by slow injection or by infusion. One dose IV Iron replacement | Monoferric Applies only to oral form of both agents. Minor/Significance Unknown. commonly, these are "non-preferred" brand drugs. Dosing for patients who weigh 50 kg or more For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. Avoid or Use Alternate Drug. Diluted with 0.9% Sodium Chloride Injection at concentrations of 1 to 2 mg/mL, 2 doses of 300 mg/250 mL over 1.5 hrsplus1 dose of 400 mg/250 mL over 2.5 hrs. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. If you log out, you will be required to enter your username and password the next time you visit. Use (s): Iron deficiency anemia in patients with chronic kidney disease (CKD) Interaction only with oral iron administration. Avoid or Use Alternate Drug. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) Applies only to oral form of both agents. Am J Hosp Pharm. Evaluate the hematologic response (hemoglobin, ferritin, iron and transferrin saturation) at least one month following the second Feraheme infusion. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Applies only to oral form of both agents. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Monitor Closely (1)iron sucrose decreases levels of ibandronate by inhibition of GI absorption. Either increases effects of the other by pharmacodynamic synergism. Alldredge BK, Corelli RL, Ernst ME, Guglielmo BJ, eds. Discuss the risks and benefits with your doctor.This medication passes into breast milk. Applies only to oral form of both agents. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. informational and educational purposes only. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. Dose. Applies only to oral form of both agents. 2000 Jan;22(1):39-43. . iron sucrose decreases levels of minocycline by inhibition of GI absorption. No additional iron to replenish stores. https://www.uptodate.com/ (Requires subscription). Applies only to oral form of both agents. Perinatology and Obstetrical Calculators Venofer (iron sucrose injection, USP) For Intravenous Use Only INDICATION AND USAGE Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Otherwise, call a poison control center right away. Applies only to oral form of both agents. The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. In post-marketing safety studies of Venofer in 1,051 patients with HDD-CKD, adverse reactions reported by >1% were cardiac failure congestive, sepsis and dysgeusia. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. Only administer Venofer when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. Applies only to oral form of both agents. Use Caution/Monitor. Applies only to oral form of both agents. Minor/Significance Unknown. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 Hb in g/dL) x 2.145, Volume of product required in mL = Iron deficit in mg / C in mg/mL. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Calculates iron deficit for dosing iron. Venofer (iron sucrose) dose calculator | Calculosaurus.com Estimates the iron deficit in preparation for iron replacement based on patient weight and haemoglobin. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. IDA diagnosis is based on full blood examination and on the serum ferritin level. Contraindicated. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. Generic name: IRON SUCROSE 20mg in 1mL Medicinal forms Applies only to oral form of both agents. There is in depth information below the form on the method used and on the result provided. (1970) Intravenous iron-dextran: therapeutic and experimental possibilities. A patients lean body weight (or actual body weight if less than lean body weight) should be utilized when determining dosage. In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . Fatal reactions have followed the test dose of iron dextran injection. Iron sucrose | Drugs | BNF | NICE Both the 200- and 300-mg doses of IV iron sucrose administered over 2 hours appear to be safe. Fulminant symptoms include confusion, sensation of passing out, paleness. Applies only to oral form of both agents. 2 *Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with CKD. Monitor Closely (1)sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Minor (2)calcium gluconate decreases levels of iron sucrose by inhibition of GI absorption. Monitor Closely (1)lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. The dosing of Monofer was performed according to the Simplified Table as described in section 4.2 above and dosing of iron sucrose was calculated according to Ganzoni and administered as 200 mg infusions. Applies only to oral form of both agents. Can't find what you need? Applies only to oral form of both agents. Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. 1) Ganzoni AM. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Drug class: Iron products. Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Calculation of the Total Iron Deficit Alternative equation, Iron Dextran Dosing Calculator (iron deficit), HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication, Pharmacosmos A/S, CosmoFer low molecular weight (Mw) iron dextran. A target haemoglobin value is also input so iron deficit can be determined according to a specified individual target. Separate dosing of tetracyclines from these products. 1000 mg. 20 MINUTES. DailyMed - VENOFER- iron sucrose injection, solution Maximum single dose of iron sucrose to be given at a time in Non-dialysis CKD patients is 500 mg but with limited experience. Administer Venofer early during the dialysis session (generally within the first hour). If we don't have the calculator you need we'll try to make it for you and add it to the website. Sodium ferric gluconate complex injection [ Ferrlecit ] [package insert] - Elemental iron: 12.5 mg/mL (5 mL). Intravenous iron sucrose for children with iron deficiency anemia: a Dosing and Infusion Rates - PRIVIGEN 10th ed. PDF IRON PRODUCT CHOICE AND DOSE CALCULATION - Blood Monitor Closely (1)sodium sulfate/?magnesium sulfate/potassium chloride decreases levels of iron sucrose by inhibition of GI absorption. Give each dose as 750 mg for a total cumulative dose not to exceed 1500 mg of iron per course. Most Intravenous Iron Therapy in Patients with Iron Deficiency Anemia Applies only to oral form of both agents. Use Caution/Monitor. Applies only to oral form of both agents. Use Caution/Monitor. Monitor Closely (1)sodium bicarbonate will decrease the level or effect of iron sucrose by increasing gastric pH. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Use Caution/Monitor. Slowing the infusion rate may alleviate symptoms. Applies only to oral form of both agents. Do Not Copy, Distribute or otherwise Disseminate without express permission. Applies only to oral form of both agents. Use Caution/Monitor. Monitor Closely (1)didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling (16.2).] For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. Steps on how to print your input & results: 1. This may be helped by giving the medication more slowly or at a lower dose. Calculation of Dosage of Nefrofer Total Iron Deficit (mg) Nefrofer (ml) = 20mg/ml Total Iron Deficit (mg) = Body weight (kg) x (Target Hb - Actual Hb) [g/l] x 0.24* + Depot Iron . VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . 1996 Aug;11(4):139-46. Accessed: 4/12/2011. If you have private insurance, Venofer or Monoferric may be on the list of covered medications. Avoid or Use Alternate Drug. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Applies only to oral form of both agents. Minor (2)calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. trientine, iron sucrose. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. Ferric carboxymaltose (Ferinject) for iron-deficiency anaemia The Ganzoni equation used by the iron deficiency calculator is the following: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. Prior to and at regular intervals during parenteral iron therapy, evaluate serum iron, hemoglobin, and hematocrit. Keep all medical and lab appointments. Minor (1)iron sucrose, captopril. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. No data are available regarding overdosage of Venofer in humans. The dosage of Venofer is expressed in mg of elemental iron. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. Ganzoni Equation for Iron Deficiency Anemia - MDCalc Iron stores are input as default 500 mg on the assumption that the patient weight is greater or equal to 35 kg (77 lbs). Avoid or Use Alternate Drug. iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. *Repeat dose if iron deficiency anemia reoccurs. May increase risk of hypotension. Venofer may cause clinically significant hypotension. All you have to do is use the following formula: Liquid\ dose = Dose / Medicine\ concentration Liquid dose = Dose/M edicine concentration. Minor/Significance Unknown. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Use Caution/Monitor. Use Caution/Monitor. Equations : Total body iron deficit (mg) = body weight (kg) x (target Hb - actual Hb in g/dL) x 2.4 + iron depot (mg)** [1, 2] Iron depot: 15 mg/kg for body weight less than 35 kg 500 mg for those with a body weight greater than or equal to 35 kg Ideal Body Weight (kg) =45.5 +2.3 * (height inches - 60 inches) [3] Iron Sucrose [ Venofer ] Elemental iron: 20 mg/mL (2.5 mL, 5 mL, 10 mL) Solution, Intravenous [preservative free]: [package insert] INDICATIONS: Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with chronic kidney disease (CKD). Hypotension following administration of Venofer may be related to rate of administration and/or total dose delivered. FERAHEME Dosing & Administration - Feraheme FERAHEME has flexible dosing for your patients FERAHEME flexible scheduling gives your patients the freedom to receive the iron they need as early as 3 days apart 1 FLEXIBLE DILUTION OPTIONS 1 Dilute full contents of vial (17 mL) in 50 mL to 200 mL of: 0.9% NaCl, or 5% dextrose STORAGE 1 Learn how to store and discard medical supplies safely. Iron Sucrose (Ferogen): Indications, Dosage, Administration - Medcrine Use Caution/Monitor. Iron Deficiency Anemia: Periodic hematologic determination (hemoglobin and hematocrit) is a simple and accurate technique for monitoring hematological response, and should be used as a guide in therapy. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin, Do not mix with other medications or add to parenteral nutrition solutions for IV infusion, Do not dilute to concentrations below 1 mg/mL, Add dose to 0.9% NaCl infusion bags (PVC or non-PVC); final concentrations range is 1-2 mg of elemental iron/mL, Visually inspect for particulate matter and discoloration prior to infusion, Stable for 7 days at controlled room temperature (25C). Applies only to oral form of both agents. Reactions have occurred following the first dose or subsequent doses of Venofer. Follow your doctor's directions carefully.Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft).A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Dosing Considerations (8-10) Maximum single dose of iron sucrose in all other patients is 300 mg every week. Schweiz Med Wochenschr. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Use Caution/Monitor. Applies only to oral form of both agents. Iron Deficiency Calculator - MDApp Each mL contains 20 mg of elemental iron. Each mL contains 20 mg of elemental iron. iron sucrose increases levels of calcium citrate by enhancing GI absorption. Patients may present with shock, clinically significant hypotension, loss of consciousness and/or collapse. For patients weighing less than 50 kg (110 lb): Give Injectafer in two doses separated by at least 7 days. iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Feraheme, when added to intravenous infusion bags containing either 0.9% Sodium Chloride Injection, USP (normal saline), or 5% Dextrose Injection, USP, at concentrations of 2-8 mg elemental iron per mL, should be used immediately but may be stored at controlled room temperature (25C 2C) for up to 4 hours or refrigerated (2-8 C) for up to 48 hours. Dosing: (a) Divide calculated total cumulate dose . Applies only to oral form of both agents. Venofer (iron sucrose) dosing, indications, interactions, adverse Creating an account is free and takes less than 1 minute. Use Caution/Monitor. iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Drug Dosing in Obesity Reference Table - ClinCalc.com Monitor Closely (1)iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Fatal reactions have also occurred in situations where the test dose was tolerated. iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Hemodialysis-dependent: 0.5 mg/kg IV q2weeks for 12 weeks; not to exceed 100 mg/dose, Non-dialysis dependent or peritoneal-dependent (on erythropoietin): 0.5 mg/kg IV q4weeks for 12 weeks; not to exceed 100 mg/dose, sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, Serious hypersensitivity reactions reported, including anaphylactic-type reactions, some of which have been life-threatening and fatal, Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse, If hypersensitivity reactions or signs of intolerance occur during administration, stop infusion immediately, Monitor patients for signs and symptoms of hypersensitivity during and after administration for at least 30 minutes and until clinically stable following completion of the infusion, Animal reproduction studies of iron sucrose administered to rats and rabbits during period of organogenesis at elemental iron doses equivalent to maximum recommended human dose based on body surface area revealed no evidence of harm to the fetus; adverse outcomes in pregnancy occur regardless of health of mother or use of medications, Iron deficiency anemia during pregnancy should be treated; untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia; adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight, HD-dependent and non-dialysis-dependent CKD: Dilute with up to 100 mL of 0.9% NaCl, PD-dependent CKD: Dilute with up to 250 mL of 0.9% NaCl, Undiluted: Administer by slow IV injection over 2-5 min, Diluted solutions: Administer IV over 15 min, Undiluted: Administer by slow IV injection over 5 minutes, Diluted solutions: Administer IV over 5-60 minutes, Store in original carton at 20-25C (68-77 F); excursions permitted to 15- 30C (59-86F), Syringe: Store at room temperature (25C) or under refrigeration (4C) for up to 7 days, IV infusion: Store at room temperature (25C) for up to 7 days.
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